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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
28.18
Human Site:
Y442
Identified Species:
56.36
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
Y442
R
W
R
E
C
V
G
Y
V
N
S
N
M
E
N
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
Y444
R
W
R
E
C
V
G
Y
V
N
S
N
M
E
N
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
Y414
T
W
R
R
C
A
N
Y
V
N
G
N
M
E
N
Dog
Lupus familis
XP_546737
807
92419
Y470
R
W
R
E
C
V
S
Y
V
N
S
N
M
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
Y428
R
W
R
E
C
V
S
Y
V
N
S
N
M
E
S
Rat
Rattus norvegicus
P0C1T0
774
89178
Y437
R
W
R
E
C
V
S
Y
V
N
S
N
M
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
Y412
R
W
R
E
C
V
S
Y
V
N
N
N
M
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
Y418
R
W
R
D
C
V
R
Y
V
Q
G
N
M
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
W515
R
W
S
Q
C
V
E
W
T
N
K
K
L
G
V
Honey Bee
Apis mellifera
XP_392502
776
89056
W442
R
W
S
Q
C
V
E
W
T
N
K
K
L
G
M
Nematode Worm
Caenorhab. elegans
O16796
848
97043
V512
R
W
K
D
C
A
Q
V
P
S
T
V
L
P
L
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
G430
R
W
R
L
C
V
D
G
I
N
G
A
M
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
66.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
73.3
N.A.
33.3
33.3
20
46.6
P-Site Similarity:
100
100
66.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
N.A.
80
N.A.
53.3
53.3
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
9
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
50
0
0
17
0
0
0
0
0
0
67
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
17
9
0
0
25
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
17
17
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
0
0
25
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
9
% M
% Asn:
0
0
0
0
0
0
9
0
0
84
9
67
0
0
42
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% P
% Gln:
0
0
0
17
0
0
9
0
0
9
0
0
0
0
0
% Q
% Arg:
92
0
75
9
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
17
0
0
0
34
0
0
9
42
0
0
0
25
% S
% Thr:
9
0
0
0
0
0
0
0
17
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
84
0
9
67
0
0
9
0
0
9
% V
% Trp:
0
100
0
0
0
0
0
17
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _